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Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway.

The mesolimbic dopaminergic system has been implicated in mediating the motivational effects of opioids and other drugs of abuse. The site of action of opioids within this system and the role of endogenous opioid peptides in modulating dopamine activity therein remain unknown. Employing the techniqu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Spanagel, R, Herz, A, Shippenberg, T S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC48593/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1347943/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.6.2046
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