Two‐Pore K(+) Channel TREK‐1 Regulates Sinoatrial Node Membrane Excitability

BACKGROUND: Two‐pore K(+) channels have emerged as potential targets to selectively regulate cardiac cell membrane excitability; however, lack of specific inhibitors and relevant animal models has impeded the effort to understand the role of 2‐pore K(+) channels in the heart and their potential as a...

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Pubblicato in:J Am Heart Assoc
Autori principali: Unudurthi, Sathya D., Wu, Xiangqiong, Qian, Lan, Amari, Foued, Onal, Birce, Li, Ning, Makara, Michael A., Smith, Sakima A., Snyder, Jedidiah, Fedorov, Vadim V., Coppola, Vincenzo, Anderson, Mark E., Mohler, Peter J., Hund, Thomas J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2016
Soggetti:
Original Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859279/
https://ncbi.nlm.nih.gov/pubmed/27098968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.115.002865
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