Ankyrin-G Coordinates Intercalated Disc Signaling Platform to Regulate Cardiac Excitability In Vivo

RATIONALE: Na(v)1.5 (SCN5A) is the primary cardiac voltage-gated Na(v) channel. Na(v)1.5 is critical for cardiac excitability and conduction, and human SCN5A mutations cause sinus node dysfunction, atrial fibrillation, conductional abnormalities, and ventricular arrhythmias. Further, defects in Na(v...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Circ Res
Autori principali: Makara, Michael A., Curran, Jerry, Little, Sean C., Musa, Hassan, Polina, Iuliia, Smith, Sakima A., Wright, Patrick J., Unudurthi, Sathya D., Snyder, Jed, Bennett, Vann, Hund, Thomas J., Mohler, Peter J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224970/
https://ncbi.nlm.nih.gov/pubmed/25239140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.305154
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi