Ankyrin-G Coordinates Intercalated Disc Signaling Platform to Regulate Cardiac Excitability In Vivo

RATIONALE: Na(v)1.5 (SCN5A) is the primary cardiac voltage-gated Na(v) channel. Na(v)1.5 is critical for cardiac excitability and conduction, and human SCN5A mutations cause sinus node dysfunction, atrial fibrillation, conductional abnormalities, and ventricular arrhythmias. Further, defects in Na(v...

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Publicado no:Circ Res
Main Authors: Makara, Michael A., Curran, Jerry, Little, Sean C., Musa, Hassan, Polina, Iuliia, Smith, Sakima A., Wright, Patrick J., Unudurthi, Sathya D., Snyder, Jed, Bennett, Vann, Hund, Thomas J., Mohler, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224970/
https://ncbi.nlm.nih.gov/pubmed/25239140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.305154
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