Ankyrin-G Coordinates Intercalated Disc Signaling Platform to Regulate Cardiac Excitability In Vivo

RATIONALE: Na(v)1.5 (SCN5A) is the primary cardiac voltage-gated Na(v) channel. Na(v)1.5 is critical for cardiac excitability and conduction, and human SCN5A mutations cause sinus node dysfunction, atrial fibrillation, conductional abnormalities, and ventricular arrhythmias. Further, defects in Na(v...

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Bibliografske podrobnosti
izdano v:Circ Res
Main Authors: Makara, Michael A., Curran, Jerry, Little, Sean C., Musa, Hassan, Polina, Iuliia, Smith, Sakima A., Wright, Patrick J., Unudurthi, Sathya D., Snyder, Jed, Bennett, Vann, Hund, Thomas J., Mohler, Peter J.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4224970/
https://ncbi.nlm.nih.gov/pubmed/25239140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.305154
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