Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveals a Mechanism for Regulation of Tumor Progression

The G-protein-coupled chemokine receptor CXCR4 generates signals that lead to cell migration, cell proliferation, and other survival mechanisms that result in the metastatic spread of primary tumor cells to distal organs. Numerous studies have demonstrated that CXCR4 can form homodimers or can heter...

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Udgivet i:J Biol Chem
Main Authors: Coke, Christopher J., Scarlett, Kisha A., Chetram, Mahandranauth A., Jones, Kia J., Sandifer, Brittney J., Davis, Ahriea S., Marcus, Adam I., Hinton, Cimona V.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859002/
https://ncbi.nlm.nih.gov/pubmed/26841863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712661
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