Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveals a Mechanism for Regulation of Tumor Progression

The G-protein-coupled chemokine receptor CXCR4 generates signals that lead to cell migration, cell proliferation, and other survival mechanisms that result in the metastatic spread of primary tumor cells to distal organs. Numerous studies have demonstrated that CXCR4 can form homodimers or can heter...

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Vydáno v:J Biol Chem
Hlavní autoři: Coke, Christopher J., Scarlett, Kisha A., Chetram, Mahandranauth A., Jones, Kia J., Sandifer, Brittney J., Davis, Ahriea S., Marcus, Adam I., Hinton, Cimona V.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4859002/
https://ncbi.nlm.nih.gov/pubmed/26841863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.712661
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