Kindlin-3 Is Essential for the Resting α4β1 Integrin-mediated Firm Cell Adhesion under Shear Flow Conditions

Integrin-mediated rolling and firm cell adhesion are two critical steps in leukocyte trafficking. Integrin α4β1 mediates a mixture of rolling and firm cell adhesion on vascular cell adhesion molecule-1 (VCAM-1) when in its resting state but only supports firm cell adhesion upon activation. The trans...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Lu, Ling, Lin, ChangDong, Yan, ZhanJun, Wang, Shu, Zhang, YouHua, Wang, ShiHui, Wang, JunLei, Liu, Cui, Chen, JianFeng
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858982/
https://ncbi.nlm.nih.gov/pubmed/26994136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.717694
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