Bacterial Interactomes: Interacting Protein Partners Share Similar Function and Are Validated in Independent Assays More Frequently Than Previously Reported

Numerous affinity purification-mass spectrometry (AP-MS) and yeast two-hybrid screens have each defined thousands of pairwise protein-protein interactions (PPIs), most of which are between functionally unrelated proteins. The accuracy of these networks, however, is under debate. Here, we present an...

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Detalhes bibliográficos
Publicado no:Mol Cell Proteomics
Main Authors: Shatsky, Maxim, Allen, Simon, Gold, Barbara L., Liu, Nancy L., Juba, Thomas R., Reveco, Sonia A., Elias, Dwayne A., Prathapam, Ramadevi, He, Jennifer, Yang, Wenhong, Szakal, Evelin D., Liu, Haichuan, Singer, Mary E., Geller, Jil T., Lam, Bonita R., Saini, Avneesh, Trotter, Valentine V., Hall, Steven C., Fisher, Susan J., Brenner, Steven E., Chhabra, Swapnil R., Hazen, Terry C., Wall, Judy D., Witkowska, H. Ewa, Biggin, Mark D., Chandonia, John-Marc, Butland, Gareth
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858938/
https://ncbi.nlm.nih.gov/pubmed/26873250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M115.054692
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