Improving the N-terminal diversity of sansanmycin through mutasynthesis

BACKGROUND: Sansanmycins are uridyl peptide antibiotics (UPAs), which are inhibitors of translocase I (MraY) and block the bacterial cell wall biosynthesis. They have good antibacterial activity against Pseudomonas aeruginosa and Mycobacterium tuberculosis strains. The biosynthetic gene cluster of s...

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Detalhes bibliográficos
Publicado no:Microb Cell Fact
Main Authors: Shi, Yuanyuan, Jiang, Zhibo, Lei, Xuan, Zhang, Ningning, Cai, Qiang, Li, Qinglian, Wang, Lifei, Si, Shuyi, Xie, Yunying, Hong, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858918/
https://ncbi.nlm.nih.gov/pubmed/27154005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0471-1
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