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SsaA, a Member of a Novel Class of Transcriptional Regulators, Controls Sansanmycin Production in Streptomyces sp. Strain SS through a Feedback Mechanism

Sansanmycins, produced by Streptomyces sp. strain SS, are uridyl peptide antibiotics with activities against Pseudomonas aeruginosa and multidrug-resistant Mycobacterium tuberculosis. In this work, the biosynthetic gene cluster of sansanmycins, comprised of 25 open reading frames (ORFs) showing cons...

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Detalhes bibliográficos
Main Authors: Li, Qinglian, Wang, Lifei, Xie, Yunying, Wang, Songmei, Chen, Ruxian, Hong, Bin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3650532/
https://ncbi.nlm.nih.gov/pubmed/23475969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00054-13
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