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Tree inference for single-cell data
Understanding the mutational heterogeneity within tumors is a keystone for the development of efficient cancer therapies. Here, we present SCITE, a stochastic search algorithm to identify the evolutionary history of a tumor from noisy and incomplete mutation profiles of single cells. SCITE comprises...
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| Publié dans: | Genome Biol |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2016
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858868/ https://ncbi.nlm.nih.gov/pubmed/27149953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0936-x |
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