RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells

BACKGROUND: Embryonic stem cells are intrinsically unstable and differentiate spontaneously if they are not shielded from external stimuli. Although the nature of such instability is still controversial, growing evidence suggests that protein translation control may play a crucial role. RESULTS: We...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Genome Biol
Κύριοι συγγραφείς: Pandolfini, Luca, Luzi, Ettore, Bressan, Dario, Ucciferri, Nadia, Bertacchi, Michele, Brandi, Rossella, Rocchiccioli, Silvia, D’Onofrio, Mara, Cremisi, Federico
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BioMed Central 2016
Θέματα:
Research
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858858/
https://ncbi.nlm.nih.gov/pubmed/27154007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0952-x
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