RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells

BACKGROUND: Embryonic stem cells are intrinsically unstable and differentiate spontaneously if they are not shielded from external stimuli. Although the nature of such instability is still controversial, growing evidence suggests that protein translation control may play a crucial role. RESULTS: We...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Pandolfini, Luca, Luzi, Ettore, Bressan, Dario, Ucciferri, Nadia, Bertacchi, Michele, Brandi, Rossella, Rocchiccioli, Silvia, D’Onofrio, Mara, Cremisi, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858858/
https://ncbi.nlm.nih.gov/pubmed/27154007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0952-x
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