RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells

BACKGROUND: Embryonic stem cells are intrinsically unstable and differentiate spontaneously if they are not shielded from external stimuli. Although the nature of such instability is still controversial, growing evidence suggests that protein translation control may play a crucial role. RESULTS: We...

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Bibliografiske detaljer
Udgivet i:Genome Biol
Main Authors: Pandolfini, Luca, Luzi, Ettore, Bressan, Dario, Ucciferri, Nadia, Bertacchi, Michele, Brandi, Rossella, Rocchiccioli, Silvia, D’Onofrio, Mara, Cremisi, Federico
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858858/
https://ncbi.nlm.nih.gov/pubmed/27154007
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0952-x
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