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Systematic analysis of somatic mutations driving cancer: uncovering functional protein regions in disease development

BACKGROUND: Recent advances in sequencing technologies enable the large-scale identification of genes that are affected by various genetic alterations in cancer. However, understanding tumor development requires insights into how these changes cause altered protein function and impaired network regu...

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Bibliografiske detaljer
Udgivet i:Biol Direct
Main Authors: Mészáros, Bálint, Zeke, András, Reményi, Attila, Simon, István, Dosztányi, Zsuzsanna
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858844/
https://ncbi.nlm.nih.gov/pubmed/27150584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13062-016-0125-6
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