Mapping Local Cytosolic Enzymatic Activity in Human Esophageal Mucosa with Porous Silicon Nanoneedles

Porous silicon nanoneedles can map Cathepsin B activity across normal and tumor human esophageal mucosa. Assembling a peptide‐based Cathepsin B cleavable sensor over a large array of nano­needles allows the discrimination of cancer cells from healthy ones in mixed culture. The same sensor applied to...

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Bibliografiske detaljer
Udgivet i:Adv Mater
Main Authors: Chiappini, Ciro, Campagnolo, Paola, Almeida, Carina S., Abbassi‐Ghadi, Nima, Chow, Lesley W., Hanna, George B., Stevens, Molly M.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2015
Fag:
Communications
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858817/
https://ncbi.nlm.nih.gov/pubmed/26197973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adma.201501304
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