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Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization

The controlled delivery of nucleic acids to selected tissues remains an inefficient process mired by low transfection efficacy, poor scalability because of varying efficiency with cell type and location, and questionable safety as a result of toxicity issues arising from the typical materials and pr...

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Detalhes bibliográficos
Publicado no:Nat Mater
Main Authors: Chiappini, C., De Rosa, E., Martinez, J. O., Liu, X., Steele, J., Stevens, M. M., Tasciotti, E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538992/
https://ncbi.nlm.nih.gov/pubmed/25822693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4249
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