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Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization

The controlled delivery of nucleic acids to selected tissues remains an inefficient process mired by low transfection efficacy, poor scalability because of varying efficiency with cell type and location, and questionable safety as a result of toxicity issues arising from the typical materials and pr...

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Bibliografiska uppgifter
I publikationen:Nat Mater
Huvudupphovsmän: Chiappini, C., De Rosa, E., Martinez, J. O., Liu, X., Steele, J., Stevens, M. M., Tasciotti, E.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538992/
https://ncbi.nlm.nih.gov/pubmed/25822693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4249
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