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Orderly progression through S-phase requires dynamic ubiquitylation and deubiquitylation of PCNA
Proliferating-cell nuclear antigen (PCNA) is a DNA sliding clamp with an essential function in DNA replication and a key role in tolerance to DNA damage by ensuring the bypass of lesions. In eukaryotes, DNA damage tolerance is regulated by ubiquitylation of lysine 164 of PCNA through a well-known co...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4858703/ https://ncbi.nlm.nih.gov/pubmed/27151298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep25513 |
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