Epithelial-to-mesenchymal transition in pancreatic ductal adenocarcinoma: Characterization in a 3D-cell culture model

AIM: To analyze the effect of three-dimensional (3D)-arrangement on the expression of epithelial-to-mesenchymal transition markers in pancreatic adenocarcinoma (PDAC) cells. METHODS: HPAF-II, HPAC, and PL45 PDAC cells were cultured in either 2D-monolayers or 3D-spheroids. Ultrastructure was analyzed...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Gagliano, Nicoletta, Celesti, Giuseppe, Tacchini, Lorenza, Pluchino, Stefano, Sforza, Chiarella, Rasile, Marco, Valerio, Vincenza, Laghi, Luigi, Conte, Vincenzo, Procacci, Patrizia
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2016
Assuntos:
Basic Study
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858630/
https://ncbi.nlm.nih.gov/pubmed/27182158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i18.4466
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