The role of epithelial to mesenchymal transition in resistance to epidermal growth factor receptor tyrosine kinase inhibitors in non-small cell lung cancer

Inhibition of the epidermal growth factor receptor (EGFR) is an important strategy when treating non-small cell lung cancer (NSCLC) patients. However, intrinsic resistance or development of resistance during the course of treatment constitutes a major challenge. The knowledge on EGFR-directed tyrosi...

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Vydáno v:Transl Lung Cancer Res
Hlavní autoři: Jakobsen, Kristine Raaby, Demuth, Christina, Sorensen, Boe Sandahl, Nielsen, Anders Lade
Médium: Artigo
Jazyk:Inglês
Vydáno: AME Publishing Company 2016
Témata:
Review Article on Non-Small Cell Lung Cancer
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858579/
https://ncbi.nlm.nih.gov/pubmed/27186512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/tlcr.2016.04.07
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