The case-only test for gene-environment interaction is not uniformly powerful: an empirical example

The case-only test has been proposed as a more powerful approach to detect gene-environment (G×E) interactions. This approach assumes that the genetic and environmental factors are independent. While it is well known that Type I error rate will increase if this assumption is violated, it is less wid...

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Pubblicato in:Genet Epidemiol
Autori principali: Wu, Chen, Chang, Jiang, Ma, Baoshan, Miao, Xiaoping, Zhou, Yifeng, Liu, Yu, Li, Yun, Wu, Tangchun, Hu, Zhibin, Shen, Hongbing, Jia, Weihua, Zeng, Yixin, Lin, Dongxin, Kraft, Peter
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858433/
https://ncbi.nlm.nih.gov/pubmed/23595356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/gepi.21713
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