Organophosphate Pesticide Exposures, Nitric Oxide Synthase Gene Variants, and Gene–Pesticide Interactions in a Case–Control Study of Parkinson’s Disease, California (USA)

BACKGROUND: Nitric oxide synthase (NOS) genes are candidates for Parkinson’s disease (PD) because NOS enzymes produce nitric oxide (NO), a pro-oxidant that can damage neurons. Widely used organophosphate (OP) pesticides can induce oxidative stress and are reported to increase PD risk. Additionally,...

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Publicado en:Environ Health Perspect
Main Authors: Paul, Kimberly C., Sinsheimer, Janet S., Rhodes, Shannon L., Cockburn, Myles, Bronstein, Jeff, Ritz, Beate
Formato: Artigo
Idioma:Inglês
Publicado: National Institute of Environmental Health Sciences 2015
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Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4858402/
https://ncbi.nlm.nih.gov/pubmed/26383258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408976
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