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Functional Paraoxonase 1 variants modify the risk of Parkinson’s Disease due to Organophosphate Exposure

BACKGROUND: We previously demonstrated that carriers of the “slower metabolizer” MM genotype of paraoxonase (PON1) who were also exposed to ambient organophosphate (OP) pesticides at their residences were at increased risk of developing Parkinson’s disease (PD). Here, with a larger sample size, we e...

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書誌詳細
主要な著者: Lee, Pei-Chen, Rhodes, Shannon L., Sinsheimer, Janet S., Bronstein, Jeff, Ritz, Beate
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690300/
https://ncbi.nlm.nih.gov/pubmed/23602893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envint.2013.03.004
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