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Functional Paraoxonase 1 variants modify the risk of Parkinson’s Disease due to Organophosphate Exposure

BACKGROUND: We previously demonstrated that carriers of the “slower metabolizer” MM genotype of paraoxonase (PON1) who were also exposed to ambient organophosphate (OP) pesticides at their residences were at increased risk of developing Parkinson’s disease (PD). Here, with a larger sample size, we e...

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Autors principals: Lee, Pei-Chen, Rhodes, Shannon L., Sinsheimer, Janet S., Bronstein, Jeff, Ritz, Beate
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3690300/
https://ncbi.nlm.nih.gov/pubmed/23602893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.envint.2013.03.004
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