N-acetylcysteine alleviates angiotensin II-mediated renal fibrosis in mouse obstructed kidneys

AIM: To investigate the effects of ROS scavenger N-acetylcysteine (NAC) on angiotensin II (Ang II)-mediated renal fibrosis in vivo and in vitro. METHODS: Mice were subjected to unilateral ureteral obstruction (UUO), and then treated with vehicle or NAC (250 mg/kg, ip) for 7 days. Histological change...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Acta Pharmacol Sin
Main Authors: Shen, Yang, Miao, Nai-jun, Xu, Jin-lan, Gan, Xin-xin, Xu, Dan, Zhou, Li, Xue, Hong, Zhang, Wei, Lu, Li-min
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857549/
https://ncbi.nlm.nih.gov/pubmed/27041464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.12
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados