A Borrelia burgdorferi Surface-Exposed Transmembrane Protein Lacking Detectable Immune Responses Supports Pathogen Persistence and Constitutes a Vaccine Target

Borrelia burgdorferi harbors a limited set of transmembrane surface proteins, most of which constitute key targets of humoral immune responses. Here we show that BB0405, a conserved membrane-spanning protein of unknown function, fails to evoke detectable antibody responses despite its extracellular...

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Publicat a:J Infect Dis
Autors principals: Kung, Faith, Kaur, Simarjot, Smith, Alexis A., Yang, Xiuli, Wilder, Cara N., Sharma, Kavita, Buyuktanir, Ozlem, Pal, Utpal
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Major Articles and Brief Reports
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857468/
https://ncbi.nlm.nih.gov/pubmed/26747708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw013
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