A Borrelia burgdorferi Surface-Exposed Transmembrane Protein Lacking Detectable Immune Responses Supports Pathogen Persistence and Constitutes a Vaccine Target

Borrelia burgdorferi harbors a limited set of transmembrane surface proteins, most of which constitute key targets of humoral immune responses. Here we show that BB0405, a conserved membrane-spanning protein of unknown function, fails to evoke detectable antibody responses despite its extracellular...

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Библиографические подробности
Опубликовано в: :J Infect Dis
Главные авторы: Kung, Faith, Kaur, Simarjot, Smith, Alexis A., Yang, Xiuli, Wilder, Cara N., Sharma, Kavita, Buyuktanir, Ozlem, Pal, Utpal
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Major Articles and Brief Reports
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857468/
https://ncbi.nlm.nih.gov/pubmed/26747708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw013
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