Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease with different molecular characteristics associated with many variables such as the sites from which the tumors originate or the presence or absence of chromosomal instability. Identification of such variables, particularly mutational ho...

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發表在:J Transl Med
Main Authors: Dallol, Ashraf, Buhmeida, Abdelbaset, Al-Ahwal, Mahmoud Shaheen, Al-Maghrabi, Jaudah, Bajouh, Osama, Al-Khayyat, Shadi, Alam, Rania, Abusanad, Atlal, Turki, Rola, Elaimi, Aisha, Alhadrami, Hani A., Abuzenadah, Mohammed, Banni, Huda, Al-Qahtani, Mohammed H., Abuzenadah, Adel M.
格式: Artigo
語言:Inglês
出版: BioMed Central 2016
主題:
Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857423/
https://ncbi.nlm.nih.gov/pubmed/27146902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0878-9
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