Clinical significance of frequent somatic mutations detected by high-throughput targeted sequencing in archived colorectal cancer samples

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous disease with different molecular characteristics associated with many variables such as the sites from which the tumors originate or the presence or absence of chromosomal instability. Identification of such variables, particularly mutational ho...

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Dades bibliogràfiques
Publicat a:J Transl Med
Autors principals: Dallol, Ashraf, Buhmeida, Abdelbaset, Al-Ahwal, Mahmoud Shaheen, Al-Maghrabi, Jaudah, Bajouh, Osama, Al-Khayyat, Shadi, Alam, Rania, Abusanad, Atlal, Turki, Rola, Elaimi, Aisha, Alhadrami, Hani A., Abuzenadah, Mohammed, Banni, Huda, Al-Qahtani, Mohammed H., Abuzenadah, Adel M.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857423/
https://ncbi.nlm.nih.gov/pubmed/27146902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0878-9
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