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Absence of cytoglobin promotes multiple organ abnormalities in aged mice

Cytoglobin (Cygb) was identified in hepatic stellate cells (HSCs) and pericytes of all organs; however, the effects of Cygb on cellular functions remain unclear. Here, we report spontaneous and age-dependent malformations in multiple organs of Cygb(−/−) mice. Twenty-six percent of young Cygb(−/−) mi...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Thuy, Le Thi Thanh, Van Thuy, Tuong Thi, Matsumoto, Yoshinari, Hai, Hoang, Ikura, Yoshihiro, Yoshizato, Katsutoshi, Kawada, Norifumi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4857093/
https://ncbi.nlm.nih.gov/pubmed/27146058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep24990
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