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ConBind: motif-aware cross-species alignment for the identification of functional transcription factor binding sites

Eukaryotic gene expression is regulated by transcription factors (TFs) binding to promoter as well as distal enhancers. TFs recognize short, but specific binding sites (TFBSs) that are located within the promoter and enhancer regions. Functionally relevant TFBSs are often highly conserved during evo...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Lelieveld, Stefan H., Schütte, Judith, Dijkstra, Maurits J.J., Bawono, Punto, Kinston, Sarah J., Göttgens, Berthold, Heringa, Jaap, Bonzanni, Nicola
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856970/
https://ncbi.nlm.nih.gov/pubmed/26721389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1518
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