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ConBind: motif-aware cross-species alignment for the identification of functional transcription factor binding sites

Eukaryotic gene expression is regulated by transcription factors (TFs) binding to promoter as well as distal enhancers. TFs recognize short, but specific binding sites (TFBSs) that are located within the promoter and enhancer regions. Functionally relevant TFBSs are often highly conserved during evo...

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Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Lelieveld, Stefan H., Schütte, Judith, Dijkstra, Maurits J.J., Bawono, Punto, Kinston, Sarah J., Göttgens, Berthold, Heringa, Jaap, Bonzanni, Nicola
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856970/
https://ncbi.nlm.nih.gov/pubmed/26721389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1518
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