Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents

Dicer participates in heterochromatin formation in fission yeast and plants. However, whether it has a similar role in mammals remains controversial. Here we showed that the human Dicer protein interacts with SIRT7, an NAD(+)-dependent H3K18Ac (acetylated lysine 18 of histone H3) deacetylase, and ho...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Zhang, Pei-Ying, Li, Guiling, Deng, Zhu-Jun, Liu, Li-Yuan, Chen, Li, Tang, Jun-Zhou, Wang, Yu-Qun, Cao, Su-Ting, Fang, Yu-Xiao, Wen, Fuping, Xu, Yunsheng, Chen, Xiaoming, Shi, Ke-Qing, Li, Wen-Feng, Xie, Congying, Tang, Kai-Fu
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856966/
https://ncbi.nlm.nih.gov/pubmed/26704979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1504
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