Therapeutic effects of the artemisinin analog SM934 on lupus-prone MRL/lpr mice via inhibition of TLR-triggered B-cell activation and plasma cell formation

We previously reported that SM934, a water-soluble artemisinin derivative, was a viable treatment in murine lupus models. In the current study, we further investigated the therapeutic effects of a modified dosage regimen of SM934 on lupus-prone MRL/lpr mice and explored its effects on B cell respons...

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Bibliografiske detaljer
Udgivet i:Cell Mol Immunol
Main Authors: Wu, Yanwei, He, Shijun, Bai, Bingxin, Zhang, Luyao, Xue, Lu, Lin, Zemin, Yang, Xiaoqian, Zhu, Fenghua, He, Peilan, Tang, Wei, Zuo, Jianping
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856803/
https://ncbi.nlm.nih.gov/pubmed/25942599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2015.13
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