The Nuclear Receptor, RORγ, Regulates Pathways Necessary for Breast Cancer Metastasis

We have previously reported that RORγ expression was decreased in ER − ve breast cancer, and increased expression improves clinical outcomes. However, the underlying RORγ dependent mechanisms that repress breast carcinogenesis have not been elucidated. Here we report that RORγ negatively regulates t...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Oh, Tae Gyu, Wang, Shu-Ching M., Acharya, Bipul R., Goode, Joel M., Graham, J. Dinny, Clarke, Christine L., Yap, Alpha S., Muscat, George E.O.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856749/
https://ncbi.nlm.nih.gov/pubmed/27211549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2016.02.028
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