Dysregulation of miRNA-9 in a subset of schizophrenia patient-derived neural progenitor cells

Converging evidence indicates that microRNAs (miRNAs) may contribute to disease risk for schizophrenia (SZ). We show that miR-9 was abundantly expressed in control NPCs, but also significantly down-regulated in a subset of SZ NPCs. We observed a strong correlation between miR-9 expression and miR-9...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Topol, Aaron, Zhu, Shijia, Hartley, Brigham J., English, Jane, Hauberg, Mads E., Readhead, Ben, Tran, Ngoc, Rittenhouse, Chelsea Ann, Simone, Anthony, Ruderfer, Douglas M., Johnson, Jessica, Hadas, Yoav, Gochman, Peter A., Wang, Ying-Chih, Shah, Hardik, Cagney, Gerard, Rapoport, Judith, Gage, Fred H., Dudley, Joel T., Sklar, Pamela, Mattheisen, Manuel, Cotter, David, Fang, Gang, Brennand, Kristen J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856588/
https://ncbi.nlm.nih.gov/pubmed/27117414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.090
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