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A Luciferase-Expressing Leishmania braziliensis Line That Leads to Sustained Skin Lesions in BALB/c Mice and Allows Monitoring of Miltefosine Treatment Outcome

BACKGROUND: Leishmania braziliensis is the most prevalent species isolated from patients displaying cutaneous and muco-cutaneous leishmaniasis in South America. However, there are difficulties for studying L. braziliensis pathogenesis or response to chemotherapy in vivo due to the natural resistance...

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Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Coelho, Adriano C., Oliveira, Jordana C., Espada, Caroline R., Reimão, Juliana Q., Trinconi, Cristiana T., Uliana, Silvia R. B.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856402/
https://ncbi.nlm.nih.gov/pubmed/27144739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004660
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