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Efficient Coalescent Simulation and Genealogical Analysis for Large Sample Sizes

A central challenge in the analysis of genetic variation is to provide realistic genome simulation across millions of samples. Present day coalescent simulations do not scale well, or use approximations that fail to capture important long-range linkage properties. Analysing the results of simulation...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:PLoS Comput Biol
Päätekijät: Kelleher, Jerome, Etheridge, Alison M, McVean, Gilean
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4856371/
https://ncbi.nlm.nih.gov/pubmed/27145223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004842
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