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The HIST1 Locus Escapes Reprogramming in Cloned Bovine Embryos
Epigenetic reprogramming is necessary in somatic cell nuclear transfer (SCNT) embryos in order to erase the differentiation-associated epigenetic marks of donor cells. However, such epigenetic memories often persist throughout the course of clonal development, thus decreasing cloning efficiency. Her...
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Veröffentlicht in: | G3 (Bethesda) |
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Hauptverfasser: | , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Genetics Society of America
2016
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856087/ https://ncbi.nlm.nih.gov/pubmed/26976441 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.115.026666 |
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