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Regulation and therapeutic targeting of peptide-activated receptor guanylyl cyclases
Cyclic GMP is a ubiquitous second messenger that regulates a wide array of physiologic processes such as blood pressure, long bone growth, intestinal fluid secretion, phototransduction and lipolysis. Soluble and single-membrane-spanning enzymes called guanylyl cyclases (GC) synthesize cGMP. In human...
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| Publicado no: | Pharmacol Ther |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4856048/ https://ncbi.nlm.nih.gov/pubmed/21185863 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2010.12.005 |
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