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A principal components method constrained by elementary flux modes: analysis of flux data sets

BACKGROUND: Non-negative linear combinations of elementary flux modes (EMs) describe all feasible reaction flux distributions for a given metabolic network under the quasi steady state assumption. However, only a small subset of EMs contribute to the physiological state of a given cell. RESULTS: In...

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Bibliografische gegevens
Gepubliceerd in:BMC Bioinformatics
Hoofdauteurs: von Stosch, Moritz, Rodrigues de Azevedo, Cristiana, Luis, Mauro, Feyo de Azevedo, Sebastiao, Oliveira, Rui
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855838/
https://ncbi.nlm.nih.gov/pubmed/27146133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-016-1063-0
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