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Elementary signaling modes predict the essentiality of signal transduction network components

BACKGROUND: Understanding how signals propagate through signaling pathways and networks is a central goal in systems biology. Quantitative dynamic models help to achieve this understanding, but are difficult to construct and validate because of the scarcity of known mechanistic details and kinetic p...

詳細記述

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書誌詳細
主要な著者: Wang, Rui-Sheng, Albert, Réka
フォーマット: Artigo
言語:Inglês
出版事項: BioMed Central 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070649/
https://ncbi.nlm.nih.gov/pubmed/21426566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-44
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