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Elementary signaling modes predict the essentiality of signal transduction network components

BACKGROUND: Understanding how signals propagate through signaling pathways and networks is a central goal in systems biology. Quantitative dynamic models help to achieve this understanding, but are difficult to construct and validate because of the scarcity of known mechanistic details and kinetic p...

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Bibliografiske detaljer
Main Authors: Wang, Rui-Sheng, Albert, Réka
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3070649/
https://ncbi.nlm.nih.gov/pubmed/21426566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-44
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