TET3 inhibits TGF-β1-induced epithelial-mesenchymal transition by demethylating miR-30d precursor gene in ovarian cancer cells

BACKGROUND: Abnormal DNA methylation/demethylation is recognized as a hallmark of cancer. TET (ten-eleven translocation) family members are novel DNA demethylation related proteins that dysregulate in multiple malignances. However, their effects on ovarian cancer remain to be elucidated. METHODS: Th...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Ye, Zhongxue, Li, Jie, Han, Xi, Hou, Huilian, Chen, He, Zheng, Xia, Lu, Jiaojiao, Wang, Lijie, Chen, Wei, Li, Xu, Zhao, Le
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855705/
https://ncbi.nlm.nih.gov/pubmed/27141829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-016-0350-y
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