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PER1 prevents excessive innate immune response during endotoxin-induced liver injury through regulation of macrophage recruitment in mice

The severity of acute liver failure (ALF) induced by bacterial lipopolysaccharide (LPS) is associated with the hepatic innate immune response. The core circadian molecular clock modulates the innate immune response by controlling rhythmic pathogen recognition by the innate immune system and daily va...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, T, Wang, Z, Yang, P, Xia, L, Zhou, M, Wang, S, Du, Jie, Zhang, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855679/
https://ncbi.nlm.nih.gov/pubmed/27054331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.9
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