Leptin changes differentiation fate and induces senescence in chondrogenic progenitor cells

Body weight is a component of the mechanical theory of OA (osteoarthritis) pathogenesis. Obesity was also found to be a risk factor for digital OA involving non-weight-bearing joints, which suggested that metabolism influences the occurrence and progression of OA. The metabolic origin of OA has been...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Dis
Prif Awduron: Zhao, X, Dong, Y, Zhang, J, Li, D, Hu, G, Yao, J, Li, Y, Huang, P, Zhang, M, Huang, Z, Zhang, Y, Miao, Y, Xu, Q, Li, H
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Original Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855655/
https://ncbi.nlm.nih.gov/pubmed/27077804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2016.68
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