Galectin-1 induces hepatocellular carcinoma EMT and sorafenib resistance by activating FAK/PI3K/AKT signaling

Galectin-1 (Gal-1) is involved in several pathological activities associated with tumor progression and chemoresistance, however, the role and molecular mechanism of Gal-1 activity in hepatocellular carcinoma (HCC) epithelial–mesenchymal transition (EMT) and sorafenib resistance remain enigmatic. In...

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Bibliografische gegevens
Gepubliceerd in:Cell Death Dis
Hoofdauteurs: Zhang, P-F, Li, K-S, Shen, Y-h, Gao, P-T, Dong, Z-R, Cai, J-B, Zhang, C, Huang, X-Y, Tian, M-X, Hu, Z-Q, Gao, D-M, Fan, J, Ke, A-W, Shi, G-M
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855644/
https://ncbi.nlm.nih.gov/pubmed/27100895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.324
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