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The pupylation machinery is involved in iron homeostasis by targeting the iron storage protein ferritin

The balance of sufficient iron supply and avoidance of iron toxicity by iron homeostasis is a prerequisite for cellular metabolism and growth. Here we provide evidence that, in Actinobacteria, pupylation plays a crucial role in this process. Pupylation is a posttranslational modification in which th...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Küberl, Andreas, Polen, Tino, Bott, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855571/
https://ncbi.nlm.nih.gov/pubmed/27078093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514529113
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