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Nitrogen monoxide-mediated control of ferritin synthesis: Implications for macrophage iron homeostasis

Intracellular iron homeostasis is regulated posttranscriptionally by iron regulatory proteins 1 and 2 (IRP1 and IRP2). In the absence of iron in the labile pool, IRPs bind to specific nucleotide sequences called iron responsive elements (IREs), which are located in the 5′ untranslated region of ferr...

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Detalhes bibliográficos
Main Authors: Kim, Sangwon, Ponka, Prem
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC129424/
https://ncbi.nlm.nih.gov/pubmed/12209009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192316099
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