Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies

BACKGROUND: In addition to anti-citrullinated protein antibodies (ACPAs), antibodies targeting carbamylated (i.e., homocitrullinated) proteins (anti-CarP antibodies) have been described in rheumatoid arthritis (RA). However, the extent to which anti-CarP antibodies are truly distinct from ACPA remai...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Reed, Evan, Jiang, Xia, Kharlamova, Nastya, Ytterberg, A. Jimmy, Catrina, Anca I., Israelsson, Lena, Mathsson-Alm, Linda, Hansson, Monika, Alfredsson, Lars, Rönnelid, Johan, Lundberg, Karin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855497/
https://ncbi.nlm.nih.gov/pubmed/27145822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1001-6
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