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Age-dependent differences in microglial responses to systemic inflammation are evident as early as middle age

Whereas age increases microglial inflammatory activities and impairs their ability to effectively regulate their immune response, it is unclear at what age these exaggerated responses begin. We tested the hypotheses that augmented microglial responses to inflammatory challenge are present as early a...

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Publicat a:Physiol Genomics
Autors principals: Nikodemova, Maria, Small, Alissa L., Kimyon, Rebecca S., Watters, Jyoti J.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4855213/
https://ncbi.nlm.nih.gov/pubmed/26884461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00129.2015
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